What is Innohep prescribed for?

Innohep is used together with warfarin, to treat blood clots that have occurred deep in the veins of hospitalized patients who may or may not have also experienced the occurrence of blood clots in their lungs (pulmonary embolism).

Who should not be treated with Innohep?

Innohep should not be given to those who:

• are currently experiencing major bleeding
• have a history of heparin causing the blood to have low platelets (thrombocytopenia)
• are allergic to:
  • heparin
  • sulfites
  • benzyl alcohol
  • pork products

Tell your doctor if you have any of these conditions.

Special Warnings associated with Innohep:

Using Innohep or other low molecular weight heparins (LMWHs) to reduce the risk of problems from blood clots when epidural/spinal anesthesia or spinal puncture is in use puts patients at risk of developing spinal or epidural injury (hematoma), which can result in long-term or permanent paralysis.

Innohep, like other drugs that prevent the blood from clotting, is given with extreme caution in conditions that increase risk of bleeding, such as:

• Inflammation of the heart and/or the tissue surrounding the heart
• severe uncontrolled high blood pressure
• bleeding disorders, including liver failure and certain protein deposits (amyloidosis)
• active ulcerative colitis and other disorders in the stomach and intestines
• bleeding into the brain (hemorrhagic stroke)
• recent brain, spinal or eye surgery
• when taking other medications that prevents the blood from clotting.

Innohep contains a sulfite that may cause a severe allergic reaction including life-threatening asthma if you are sensitive to sulfites.

General Precautions to take when on Innohep:

Because certain other medications can increase the risk of bleeding with Innohep, tell your doctor what medications you are taking, including those that you take without a prescription. Tell your doctor or doctor if you are taking:

• blood thinners
• salicylates, such as aspirin
• sulfinpyrazone
• dextran
• non-steroidal anti-inflammatory drugs such as ibuprofen (Motrin), naproxen sodium (Naprosyn or Alleve).

There are some things that you should tell your doctor when taking this medication:

Tell your doctor or doctor if you have a history of:

• a tendency to bleed easily
• uncontrolled high blood pressure
• recent stomach ulcer
• eye problems due to diabetes
• recent bleeding
• kidney problems
• hemorrhagic stroke

Because vials of Innohep contain the preservative benzyl alcohol, tell your doctor or doctor if you are pregnant, trying to get pregnant, or if you are currently breast feeding. Benzyl alcohol can and may cross the placenta in pregnant women and cause death in premature babies.

What side effects can you expect when taking Innohep? (This is only a partial list of side effects reported with Innohep. Ask your doctor or pharmacist for a complete list of possible side effects and drug interactions..)

The most common side effect with Innohep is bleeding.

For more detailed information about Innohep, ask your doctor.